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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.
SOURCES — epitalon-telomerase (academic graphics)
Page: Epitalon and telomerase. All imagery is openly licensed (CC0 / CC BY) or rendered by us from public-domain PDB coordinates. No CC BY-SA material used. No image was fabricated or AI-generated.
Used images
1. Human telomerase core (PDB 7BG9) — rendered by us
- What: Cartoon render of the catalytic core lobe of human telomerase in complex with a telomeric DNA substrate (protein teal, DNA amber).
- Source paper: Ghanim GE, Fountain AJ, van Roon AMM, Rangan R, Das R, Collins K, Nguyen THD. "Structure of human telomerase holoenzyme with bound telomeric DNA." Nature 2021.
- DOI: 10.1038/s41586-021-03415-4 · PMID: 33883742
- PDB entry: 7BG9 ("The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate")
- License: wwPDB coordinates are public domain; this render was produced for this page with PyMOL.
- Attribution line printed on graphic: "PDB 7BG9 · Nguyen THD, Ghanim GE et al., Nature 2021 · public-domain coordinates, rendered for this page"
2. Human telomeric DNA fold (PDB 1KF1) — rendered by us
- What: Cartoon of the human telomeric G-quadruplex.
- Source paper: Parkinson GN, Lee MPH, Neidle S. "Crystal structure of parallel quadruplexes from human telomeric DNA." Nature 2002.
- DOI: 10.1038/nature755 · PMID: 12050675
- PDB entry: 1KF1 ("Structure and Packing of Human Telomeric DNA")
- License: wwPDB coordinates are public domain; this render was produced for this page with PyMOL.
- Attribution line printed on graphic: "PDB 1KF1 · Parkinson GN et al., Nature 2002 · public-domain coordinates, rendered for this page"
3. Telomere Q-FISH (sheep oocyte)
- What: Quantitative FISH of telomeres (green dots) around the nucleolus; cropped to the micrograph panel of the original composite.
- Source file: "Ovocito. Antral temprano.. Distribución de Telómeros (puntos verdes) surrounded nucleolus SN cromatina. Diametro 20µm.png"
- Authors: Barboni B, Russo V, Cecconi S, Curini V, Colosimo A, Garofalo ML, Capacchietti G, Di Giacinto O, Bernabò N, Rendina R, Mattioli M.
- License: CC BY 3.0, via Wikimedia Commons.
- URL: https://commons.wikimedia.org/wiki/File:Ovocito.Antral_temprano.._Distribuci%C3%B3n_de_Tel%C3%B3meros(puntos_verdes)_surrounded_nucleolus_SN_cromatina._Diametro_20%C2%B5m.png
- Attribution line printed on graphic: "Barboni B et al., CC BY 3.0, via Wikimedia Commons"
4. Cultured human cells (HeLa)
- What: Scanning electron micrograph of HeLa cells in culture.
- Source file: "HeLa Cells Image 3709-PH.jpg"
- Authors: National Institutes of Health (photographer unknown).
- License: Public domain, via Wikimedia Commons.
- URL: https://commons.wikimedia.org/wiki/File:HeLa_Cells_Image_3709-PH.jpg
- Attribution line printed on graphic: "National Institutes of Health, public domain, via Wikimedia Commons"
Rejected with reasons
- CC BY-SA telomerase/telomere images on Wikimedia Commons (e.g. telomerase cartoon diagrams) — license incompatible (BY-SA excluded).
- "41467 2023 39758 Fig1.webp" (CC BY 4.0) — considered for a mitochondrial panel elsewhere; shows tick endosymbionts, not mammalian mitochondria — depiction mismatch.