Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — free-radical-aging (academic graphics)

Page: Free radicals and ageing. All imagery is openly licensed (CC0 / CC BY) or rendered by us from public-domain PDB coordinates. No CC BY-SA material used. No image was fabricated or AI-generated.

Used images

1. Mitochondria (TEM)

What: Transmission electron micrograph of mitochondria in mouse embryonic fibroblasts.
Source file: "TEM image of mitochondria in MEF OMA1-KO.png"
Authors: Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Proksch P, Peter C, Jäger S, Reichert AS, Stork B, Wesselborg S.
License: CC BY 4.0, via Wikimedia Commons.
URL: https://commons.wikimedia.org/wiki/File:TEM_image_of_mitochondria_in_MEF_OMA1-KO.png
Attribution line printed on graphic: "Böhler P et al., CC BY 4.0, via Wikimedia Commons"

2. Respiratory complex I (PDB 5XTD) — rendered by us

What: Cartoon of human mitochondrial respiratory complex I (shown within the I2III2IV2 megacomplex).
Source paper: Gu J, Wu M, Yang M. "Architecture of human mitochondrial respiratory megacomplex I2III2IV2." Cell 2017.
DOI: 10.1016/j.cell.2017.07.050 · PMID: 28844695
PDB entry: 5XTD ("Cryo-EM structure of human respiratory complex I")
License: wwPDB coordinates are public domain; this render was produced for this page with PyMOL.
Attribution line printed on graphic: "PDB 5XTD · Gu J et al., Cell 2017 · public-domain coordinates, rendered for this page"

3. Superoxide dismutase (PDB 2SOD) — rendered by us

What: Cartoon of Cu/Zn superoxide dismutase.
Source paper: Tainer JA, Getzoff ED, Beem KM, Richardson JS, Richardson DC. "Determination and analysis of the 2 Å structure of copper, zinc superoxide dismutase." J. Mol. Biol. 1982.
DOI: 10.1016/0022-2836(82)90174-7 · PMID: 7175933
PDB entry: 2SOD ("Determination and analysis of the 2 Angstrom structure of copper, zinc superoxide dismutase")
License: wwPDB coordinates are public domain; this render was produced for this page with PyMOL.
Attribution line printed on graphic: "PDB 2SOD · Tainer JA et al., J Mol Biol 1982 · public-domain coordinates, rendered for this page"

4. Senescent cells (SA-β-gal staining)

What: Senescence-associated β-galactosidase staining panels in D-gal-induced ageing rat muscle; cropped to the staining panels of the original composite figure.
Source file: "Effects of spermidine and-or exercise on the damage of gastrocnemius muscle in D-gal-induced aging rats through the evaluation of SA-β-gal staining (×40).png"
Authors: Fan J, Yang X, Li J, Shu Z, Dai J, Liu X, Li B, Jia X (authors of the study).
License: CC BY 3.0, via Wikimedia Commons.
URL: https://commons.wikimedia.org/wiki/File:Effects_of_spermidine_and-or_exercise_on_the_damage_of_gastrocnemius_muscle_in_D-gal-induced_aging_rats_through_the_evaluation_of_SA-%CE%B2-gal_staining_(%C3%9740).png
Attribution line printed on graphic: "Fan J et al., CC BY 3.0, via Wikimedia Commons"

Rejected with reasons

"41467 2023 39758 Fig1.webp" (CC BY 4.0) — considered as a mitochondrial panel; shows tick endosymbionts, not mammalian mitochondria — depiction mismatch.