Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — grey-market-glp1 (academic graphics)

Page: Grey-market GLP-1 products. All imagery is openly licensed (CC0 / CC BY) or rendered by us from public-domain PDB coordinates. No CC BY-SA material used. No image was fabricated or AI-generated.

Used images

1. GLP-1 receptor with G protein (PDB 5VAI) — rendered by us

What: Cartoon of the activated GLP-1 receptor in complex with its G protein.
Source paper: Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, Tarrasch JT, Li S, Kobilka TS, Kobilka BK, Skiniotis G. "Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein." Nature 2017.
DOI: 10.1038/nature22394 · PMID: 28538729
PDB entry: 5VAI ("Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein")
License: wwPDB coordinates are public domain; this render was produced for this page with PyMOL.
Attribution line printed on graphic: "PDB 5VAI · Zhang Y et al., Nature 2017 · public-domain coordinates, rendered for this page"

2. Pancreatic islets (insulin IHC)

What: Immunohistochemistry of rat pancreas showing insulin-positive islets of Langerhans among exocrine acini.
Source file: "Detection of insulin in the rat pancreas by immunohistochemistry.jpg"
Authors: Vladyslava Meshko.
License: CC0, via Wikimedia Commons.
URL: https://commons.wikimedia.org/wiki/File:Detection_of_insulin_in_the_rat_pancreas_by_immunohistochemistry.jpg
Attribution line printed on graphic: "Vladyslava Meshko, CC0, via Wikimedia Commons"

3. Islet cell composition (diagram)

What: Diagram of pancreatic islet cell types and their proportions in rat and human (used as a labeled diagram, not a micrograph).
Source file: "Suckale08 fig2 islet structure.jpg"
Authors: Jakob Suckale, Michele Solimena.
License: CC BY 3.0, via Wikimedia Commons.
URL: https://commons.wikimedia.org/wiki/File:Suckale08_fig2_islet_structure.jpg
Attribution line printed on graphic: "Suckale J, Solimena M, CC BY 3.0, via Wikimedia Commons"

Rejected with reasons

Several vial/medicine product photos on Commons — rejected: brand/depiction mismatch risk (they depict specific real products); drawn schematics used instead, consistent with "no branded medicine".
Any non-open GLP-1 receptor figure from review articles — rejected: not openly licensed.