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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

Sourced imagery — gut-origin-parkinsons academic infographics

Compiled 2026-10-10. Everything below is real, openly licensed scientific imagery/data. No fabricated content. Only CC0, CC-BY, or public-domain sources are used; CC BY-SA / BY-NC / BY-ND are never used.

Images (kept)

File What it shows Source DOI / PMCID License Required attribution line
sourced/alpha-synuclein-lewy-ihc-movalley.jpg Immunostaining (brown) of α-synuclein in Lewy bodies and Lewy neurites in the neocortex of a patient with Lewy body disease; Nissl counterstain (blue), 40× Wikimedia Commons user "Movalley" (own work), File:Immunostaining (brown) of alpha-synuclein in Lewy Bodies and Lewy Neurites in the neocortex of a patient with Lewy Body Disease.jpg — (no paper) CC0 Not legally required; credit as "Immunostain: Movalley, CC0, via Wikimedia Commons"
sourced/Lewy_pathology_near_an_Abeta_plaque.jpg Photomicrograph of α-synuclein in a Lewy body (upper left) and Lewy neurite (arrow) near an amyloid-β plaque (brown), brain of an elderly person who died with dementia Wikimedia Commons user "Tulemo" (own work), File:Lewy pathology near an Abeta plaque.jpg — (no paper) CC0 Not legally required; credit as "Photomicrograph: Tulemo, CC0, via Wikimedia Commons"
sourced/Fneur-10-00574-g001.jpg Published review diagram: bidirectional brain–gut interplay via vagus-nerve (VN) and non-VN (lymphatic/bloodstream) pathways Figure 1 of Santos SF, de Oliveira HL, Yamada ES, Neves BC, Pereira A Jr., "The gut and Parkinson's disease — a bidirectional pathway?" Frontiers in Neurology 2019;10:574, via Wikimedia Commons (File:Fneur-10-00574-g001.jpg) DOI 10.3389/fneur.2019.00574 CC BY 4.0 "Figure 1: Santos et al., Front Neurol 2019, CC BY 4.0, via Wikimedia Commons"
sourced/asyn-fibril-core-render.png Cα-trace tube render of the α-synuclein fibril core (PDB 2N0A, residues 35–100 shown), stacked β-sheets — rendered in-house with our own pure-Python renderer PDB entry 2N0A: Tuttle MD et al., "Structure of a Parkinson's disease α-synuclein fibril," Nature Structural & Molecular Biology 2016;23:409–415 DOI 10.1038/nsmb.3190 PDB coordinates are public domain (RCSB Protein Data Bank) Not legally required; credit as "Structure: Tuttle et al. 2016, PDB 2N0A (public domain coordinates); rendered in-house"

Rejected candidates (not kept)

Candidate Why rejected
Commons File:Lewy body and Lewy neurite (substantia nigra) variants tagged CC BY-SA Share-alike license not permitted
Published dopaminergic-pathway SVGs from Wikipedia articles CC BY-SA 4.0
File:Parkinson's disease pathophysiology.svg (hypothetical gut–brain route diagrams) CC BY-SA

Notes for the graphics build