Return to the scientific review

Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — infection-triggered-autoimmunity-academic (Track 2, academic)

Every raster image used in this page's academic graphics, with its source, license and attribution. PDB coordinates are public domain per wwPDB policy (https://www.wwpdb.org/about/pdb-data-use); ribbons were rendered by the Hypothesis Critic team from those coordinates.

Images kept

File What it shows Source paper / authors DOI / PMCID Figure License Attribution line
islet-infiltration.jpg Fig 4B crop: immunofluorescence of pancreatic islets in NOD mice — merge, CD3 (yellow), CD8 (red) across treatment groups Agapoff M, Dubreil C, Waeckel-Énée E, et al. “Proinsulin-Loaded Nanoparticles Suppress Insulitis and Induce Temporary Diabetes Remission.” Cells. 2026;15(2):174 doi:10.3390/cells15020174 · PMCID: PMC12839391 Fig 4B (cropped) CC BY 4.0 Agapoff M et al., Cells 2026, Fig 4B, CC BY 4.0
islet-detail.jpg Magnified crop of the same panel: single islet with surrounding CD3+/CD8+ cells (derived, same license) Derived from Agapoff M et al., Cells 2026, Fig 4B doi:10.3390/cells15020174 · PMCID: PMC12839391 Fig 4B (magnified crop) CC BY 4.0 Derived crop · Agapoff M et al., Cells 2026, CC BY 4.0

PDB structures rendered (public domain coordinates)

PDB Structure Rendered for
1MWA 2C T-cell receptor bound to H-2Kb MHC class I with peptide Molecular panels (TCR–MHC + detail inset)

Rejected candidates (not used)

Candidate Why rejected
Fig 5 (g005) dot plots of islet immune-cell counts from the same paper Quantification charts, not cellular imagery; Fig 4B shows the infiltration directly
H&E islet sections (Fig 4A scoring panel) Bar chart of infiltration scores; the immunofluorescence panel shows the cells