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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.
SOURCES — infection-triggered-autoimmunity-academic (Track 2, academic)
Every raster image used in this page's academic graphics, with its source, license and attribution. PDB coordinates are public domain per wwPDB policy (https://www.wwpdb.org/about/pdb-data-use); ribbons were rendered by the Hypothesis Critic team from those coordinates.
Images kept
| File | What it shows | Source paper / authors | DOI / PMCID | Figure | License | Attribution line |
|---|---|---|---|---|---|---|
islet-infiltration.jpg |
Fig 4B crop: immunofluorescence of pancreatic islets in NOD mice — merge, CD3 (yellow), CD8 (red) across treatment groups | Agapoff M, Dubreil C, Waeckel-Énée E, et al. “Proinsulin-Loaded Nanoparticles Suppress Insulitis and Induce Temporary Diabetes Remission.” Cells. 2026;15(2):174 | doi:10.3390/cells15020174 · PMCID: PMC12839391 | Fig 4B (cropped) | CC BY 4.0 | Agapoff M et al., Cells 2026, Fig 4B, CC BY 4.0 |
islet-detail.jpg |
Magnified crop of the same panel: single islet with surrounding CD3+/CD8+ cells (derived, same license) | Derived from Agapoff M et al., Cells 2026, Fig 4B | doi:10.3390/cells15020174 · PMCID: PMC12839391 | Fig 4B (magnified crop) | CC BY 4.0 | Derived crop · Agapoff M et al., Cells 2026, CC BY 4.0 |
PDB structures rendered (public domain coordinates)
| PDB | Structure | Rendered for |
|---|---|---|
| 1MWA | 2C T-cell receptor bound to H-2Kb MHC class I with peptide | Molecular panels (TCR–MHC + detail inset) |
Rejected candidates (not used)
| Candidate | Why rejected |
|---|---|
| Fig 5 (g005) dot plots of islet immune-cell counts from the same paper | Quantification charts, not cellular imagery; Fig 4B shows the infiltration directly |
| H&E islet sections (Fig 4A scoring panel) | Bar chart of infiltration scores; the immunofluorescence panel shows the cells |