Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — inflammaging-primary-driver-academic (Track 2, academic)

Every raster image used in this page's academic graphics, with its source, license and attribution. PDB coordinates are public domain per wwPDB policy (https://www.wwpdb.org/about/pdb-data-use); ribbons were rendered by the Hypothesis Critic team from those coordinates.

Images kept

File	What it shows	Source paper / authors	DOI / PMCID	Figure	License	Attribution line
`cellular-senescence-53bp1.png`	Etoposide-treated human cancer cells stained for 53BP1 (red, DNA-damage foci), tubulin (green), DAPI (blue)	Wikimedia Commons, user “Velichko Artem” (own work)	—	—	CC BY 4.0	Velichko Artem, CC BY 4.0, via Wikimedia Commons
`il1b-inflammasome-ihc.jpg`	Fig 5: fluorescence microscopy of IL-1β/GFP-transfected human astrocytes/HEK293 cells; western blot	Tarassishin L, Casper D, Lee S. “Aberrant expression of interleukin-1β and inflammasome activation in human malignant gliomas.” PLOS ONE. 2014;9(7):e103432	doi:10.1371/journal.pone.0103432 · PMCID: PMC4108401	Fig 5 (g005)	CC BY 4.0	Tarassishin L et al., PLOS ONE 2014, Fig 5, CC BY 4.0

PDB structures rendered (public domain coordinates)

PDB	Structure	Rendered for
1ALU	Interleukin-6	Molecular panels (IL-6)
1TNF	Tumor necrosis factor alpha homotrimer	Molecular panels (TNF-α)
1ITB	Interleukin-1β in complex with the type 1 IL-1 receptor	Molecular panels (IL-1β + receptor)

Rejected candidates (not used)

Candidate	Why rejected
NIH BioArt T-cell senescence diagram (public domain)	Diagram, not real data; the 53BP1 micrograph covers the senescence-trigger panel with real data