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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.
SOURCES — llps-nuclear-bodies (Track 2, academic)
All raster imagery is openly licensed: CC0 or CC-BY only. No CC BY-SA, no non-open figures.
PDB atomic coordinates are public domain (RCSB Protein Data Bank) and were rendered
for these graphics with a self-written matplotlib C-alpha trace renderer
(infographics-build/render_pdb.py). No micrograph was fabricated.
Kept
- PDB 2P1B — nucleophosmin (NPM1) core domain, pentamer
- Source: RCSB Protein Data Bank, entry 2P1B (Lee et al., crystal structure of the nucleoplasmin-like core domain of nucleophosmin).
- License: public-domain coordinates.
- Used in:
llps-nuclear-bodies-molecular-cascade.png, panels 1 and 3 (side and top views). -
Attribution line on graphic: "PDB 2P1B · public-domain coordinates, rendered for this graphic"
-
PDB 5W3N — hnRNP A2 low-complexity domain, assembled fibril
- Source: RCSB Protein Data Bank, entry 5W3N (Lu et al., atomic structure of the hnRNPA2 low-complexity domain).
- License: public-domain coordinates.
- Used in:
llps-nuclear-bodies-molecular-cascade.png, panel 2. -
Attribution line on graphic: "PDB 5W3N · public-domain coordinates, rendered for this graphic"
-
Main antinuclear antibody patterns on immunofluorescence
- Source: Wikimedia Commons,
File:Main antinuclear antibody patterns on immunofluorescence.png - Authors: Al-Mughales JA (2022); minor edits by Mikael Häggström, M.D.
- License: CC BY 4.0.
- Used in:
llps-nuclear-bodies-cellular-scene.png, panel 1. Shows speckled, homogeneous, mixed, nucleolar, centromere and peripheral nuclear staining patterns in human cells. - Attribution line on graphic: "Al-Mughales JA (2022) · Wikimedia Commons · CC BY 4.0"
Rejected
- PLOS Biology 10.1371/journal.pbio.3003775, Fig. 1 (polyphosphate-driven condensates in E. coli; CC BY 4.0) — rejected: bacterial system, wrong biological context for nuclear bodies.
- Murthy et al., Nat. Struct. Mol. Biol. 2019 (FUS LCD droplet fusion micrographs) — rejected: not open access; no CC-BY license available.
- Cells review PMC13565447, Figs. 1–2 (CC BY 4.0) — rejected: figure download blocked by publisher bot protection; figures were schematic composites rather than primary micrographs.
- Wikimedia Commons
File:NucleolusNCc.jpg— rejected: CC BY-SA 4.0 (share-alike not permitted). - Wikimedia Commons
File:DL20240202 NCL-in-T98G.tif— rejected: CC BY-SA 4.0 (share-alike not permitted).
Imagery gaps
- No openly licensed (CC0/CC-BY) micrograph of liquid-like droplet fusion in a eukaryotic nucleus was found; the molecular panels therefore rely on real protein structures and the cellular panel on real nuclear-body immunofluorescence rather than droplet micrographs.