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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — metformin-geroprotection (Track 2, academic)

All raster imagery is openly licensed: CC0 or CC-BY only. No CC BY-SA, no non-open figures. PDB atomic coordinates are public domain (RCSB Protein Data Bank) and were rendered for these graphics with a self-written matplotlib C-alpha trace renderer (infographics-build/render_pdb.py). No micrograph was fabricated.

Kept

  1. Metformin, ball-and-stick 3D model
  2. Source: Wikimedia Commons, File:Metformin-from-xtal-3D-balls.png (ball-and-stick model of C4H11N5 from X-ray crystallographic data).
  3. Authors: Ben Mills (2008-08-18).
  4. License: public domain.
  5. Used in: metformin-geroprotection-molecular-cascade.png, panel 1.
  6. Attribution line on graphic: "Ben Mills (2008) · public domain · Wikimedia Commons"

  7. PDB 4CFF — AMP-activated protein kinase (AMPK)

  8. Source: RCSB Protein Data Bank, entry 4CFF (Xiao et al., crystal structure of mammalian AMPK).
  9. License: public-domain coordinates.
  10. Used in: metformin-geroprotection-molecular-cascade.png, panels 2 and 3 (two views).
  11. Attribution line on graphic: "PDB 4CFF · public-domain coordinates, rendered for this graphic"

  12. Mitochondria in mammalian lung tissue (TEM)

  13. Source: Wikimedia Commons, File:Mitochondria, mammalian lung - TEM.jpg
  14. Authors: Louisa Howard. Thin section showing mitochondria with cristae.
  15. License: public domain.
  16. Used in: metformin-geroprotection-cellular-scene.png, panel 1.
  17. Attribution line on graphic: "Louisa Howard · public domain · Wikimedia Commons"

Rejected

Imagery gaps