Return to the scientific review

Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — microbiome-human-obesity (Track 2, academic)

All imagery is openly licensed (CC0, CC-BY, or public domain). No CC BY-SA or non-open figures used. PDB coordinates are public domain (wwPDB); structures rendered in-house with PyMOL 3.2.

microbiome-human-obesity-molecular-cascade.png

  1. TLR4–MD-2–LPS complex (PDB 3FXI) — rendered in-house (cartoon; LPS shown as sticks, magenta).
  2. Paper: Park BS, Song DH, Kim HM, Choi B-S, Lee H, Lee J-O. "The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex." Nature (2009).
  3. DOI: 10.1038/nature07830 · Method: X-ray diffraction · License: public domain (wwPDB coordinates).
  4. Attribution line: "Rendered from public-domain PDB coordinates (wwPDB) · PDB 3FXI — Park BS et al., Nature (2009)"
  5. FXR ligand-binding domain + bile-acid analogue (PDB 1OSV) — rendered in-house (cartoon; ligand sticks, magenta).
  6. Paper: Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, et al. "Structural basis for bile acid binding and activation of the nuclear receptor FXR." Mol Cell (2003).
  7. DOI: 10.1016/S1097-2765(03)00112-6 · Method: X-ray diffraction · License: public domain (wwPDB coordinates).
  8. Attribution line: "Rendered from public-domain PDB coordinates (wwPDB) · PDB 1OSV — Mi LZ et al., Mol Cell (2003)"
  9. E. coli scanning electron micrograph — sourced/ecoli-sem.jpg
  10. Authors: Photo by Eric Erbe; digital colorization by Chris Pooley, USDA.
  11. Source: https://commons.wikimedia.org/wiki/File:E_coli_at_10000x,_original.jpg · License: public domain.
  12. Attribution line: "Eric Erbe / Chris Pooley, USDA — public domain, via Wikimedia Commons"

microbiome-human-obesity-cellular-scene.png

  1. Small-intestinal villi histology — sourced/ileum-villi.jpg
  2. Author: Mikael Häggström, M.D.
  3. Source: https://commons.wikimedia.org/wiki/File:Cross-section_histology_of_small_intestinal_villi_of_the_terminal_ileum.jpg · License: CC0.
  4. Attribution line: "Mikael Häggström — CC0, via Wikimedia Commons"
  5. Human adipose tissue — sourced/adipose-human.jpg
  6. Author: Chalova.lina.
  7. Source: https://commons.wikimedia.org/wiki/File:Adipose_tissue.jpg · License: CC BY 4.0.
  8. Attribution line: "Chalova.lina — CC BY 4.0, via Wikimedia Commons"
  9. β2-tanycytes, control vs high-fat-diet mice (Fig 3) — sourced/tanycyte-hfd.png
  10. Paper: Severi I, Fosca M, Colleluori G, Marini F, Imperatori L, Senzacqua M, et al. "High-Fat Diet Impairs Mouse Median Eminence: A Study by Transmission and Scanning Electron Microscopy Coupled with Raman Spectroscopy." Int J Mol Sci 22:8049 (2021).
  11. DOI: 10.3390/ijms22158049 · Figure 3 (EM panels) · License: CC BY 4.0.
  12. Source: https://commons.wikimedia.org/wiki/File:Intracellular_ultrastructural_features_of_β2-tanycytes_from_normo-fed_controls_(CTRL)and_high-fat_diet(HFD)_mice.png
  13. Attribution line: "Severi I et al., Int J Mol Sci (2021), Fig 3 — CC BY 4.0, via Wikimedia Commons"

Rejected candidates