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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

SOURCES — mitochondrial-cascade (Track 2, academic)

All imagery is openly licensed (CC0, CC-BY, or public domain). No CC BY-SA or non-open figures used. PDB coordinates are public domain (wwPDB); structures rendered in-house with PyMOL 3.2.

mitochondrial-cascade-molecular-cascade.png

1. Mammalian mitochondrial respirasome (PDB 6G2J) — rendered in-house (cartoon, spectrum).
2. Paper: Agip AA, Blaza JN, Bridges HR, Viscomi C, Rawson S, et al. "Cryo-EM structures of complex I from mouse heart mitochondria in two sequential steps of the catalytic cycle." Nat Struct Mol Biol (2018). (PDB 6G2J: respirasome supercomplex I–III–IV.)
3. DOI: 10.1038/s41594-018-0073-1 · Method: electron microscopy · License: public domain (wwPDB coordinates).
4. Attribution line: "Rendered from public-domain PDB coordinates (wwPDB) · PDB 6G2J — Agip AA et al., Nat Struct Mol Biol (2018)"
5. Bovine mitochondrial ATP synthase, state 1a (PDB 5ARA) — rendered in-house (cartoon, spectrum).
6. Paper: Zhou A, Rohou A, Schep DG, Bason JV, Montgomery MG, et al. "Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM." eLife 4:e10180 (2015).
7. DOI: 10.7554/eLife.10180 · Method: electron microscopy · License: public domain (wwPDB coordinates).
8. Attribution line: "Rendered from public-domain PDB coordinates (wwPDB) · PDB 5ARA — Zhou A et al., eLife (2015)"

mitochondrial-cascade-cellular-scene.png

1. MEF cell mitochondria (fluorescence) — sourced/mef-mito.jpg
2. Author: Institute of Molecular Medicine I, University of Düsseldorf (own work).
3. Description: mitochondria (red, DsRed matrix stain) and nuclei (blue, DAPI) of two mouse embryonic fibroblasts.
4. Source: https://commons.wikimedia.org/wiki/File:MEF_cell_mitochondria.jpg · License: CC BY 4.0.
5. Attribution line: "Institute of Molecular Medicine I, Univ. Düsseldorf — CC BY 4.0, via Wikimedia Commons"
6. Mitophagy in Purkinje cells (EM) — sourced/mitophagy-purkinje.jpg
7. Paper: Chakrabarti L, Eng J, Ivanov N, et al. "Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death." Mol Brain 2:24 (2009).
8. DOI: 10.1186/1756-6606-2-24 · Figure: EM panels of Purkinje-cell soma (wild-type vs pcd5J).
9. Source: https://commons.wikimedia.org/wiki/File:Mitophagy_purkinje_cell.jpg · License: CC BY 3.0 (file page).
10. Attribution line: "Chakrabarti L et al., Mol Brain (2009) — CC BY 3.0, via Wikimedia Commons"

Rejected candidates

• Candidate "6VQM" initially selected as ATP synthase — verified via RCSB as human ACK1 kinase ("Crystal Structure Analysis of human ACK1"), not ATP synthase → rejected (wrong molecule); replaced with PDB 5ARA (verified bovine ATP synthase).
• "41598 2013 Article BFsrep03337 Fig2 HTML.png" — CC BY-SA 4.0 → rejected (license).
• Various "mitochondria TEM" search hits on parasite/algae papers (CC BY 4.0 but wrong biological context) → rejected (relevance).