Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.

Sources — Tumor microenvironment primacy (academic track)

All images on the two academic graphics are real, openly-licensed data. PDB coordinates are public domain. Diagrams/schematics are labeled as such on the graphics.

Images used

Cellular scene

Invasive breast carcinoma — heterogeneity
Source file: Microscopy of intratumoral morphological heterogeneity in invasive breast carcinoma.jpg
Paper: Krakhmal NV, Zavyalova MV, Denisov EV, Vtorushin SV, Perelmuter VM (2015). "Cancer Invasion: Patterns and Mechanisms." Acta Naturae 7(2):17–28, PMCID PMC4463409.
Figure: histological figure of intratumoral morphological heterogeneity (H&E micrograph).
License: CC BY 4.0 (Wikimedia Commons).
Attribution line on graphic: "Krakhmal NV et al. (2015), Acta Naturae 7(2):17–28, PMC4463409, CC BY."
The tumor microenvironment (published figure)
Source file: Tumor microenvironment.jpg
Paper: published in Frontiers in Oncology, article doi:10.3389/fonc.2013.00197 (fonc-03-00197).
License: CC BY 3.0 (Wikimedia Commons).
Attribution line on graphic: "Frontiers in Oncology, CC BY 3.0."
T cells recruited into tumors (published figure)
Source file: Regulatory T cell recruitment in tumors.jpg
Paper: Plitas G, Rudensky AY. "Regulatory T Cells: Differentiation and Function." Annual Review of Cancer Biology, doi:10.1146/annurev-cancerbio-030419-033428.
License: CC BY 4.0 (Wikimedia Commons).
Attribution line on graphic: "Plitas G, Rudensky AY, Annu Rev Cancer Biol, CC BY 4.0."

Molecular cascade (all rendered by us from public-domain PDB coordinates)

TGF-β1 — PDB 1KLA (NMR structure; model 1 shown). Rendered with our own CA-trace tube renderer.
VEGF — PDB 1VPF (NMR structure). Rendered with our own CA-trace tube renderer.
PD-L1 — PDB 5J89 (X-ray structure). Rendered with our own CA-trace tube renderer.

PDB coordinates are public domain; these panels are our own renders, not reused figures.

Rejected candidates

Several otherwise-suitable Wikimedia Commons images were rejected because they are licensed CC BY-SA, which the project policy forbids (open policy: CC0 or CC-BY only).
Figures from papers cited in the page's review HTML that are not openly licensed were rejected — their rights do not permit reuse.
No images were fabricated: no AI-generated micrographs, no invented charts or scans. Where no open imagery existed, panels were kept to molecular renders or clearly-labeled schematics.