{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Excess adiposity is a credible contributor to early-onset colorectal cancer, but its precise causal effect before50 and its share of the incidence rise remain less securely identified than the broader colorectal-cancer link.",
  "implications": "The preregistered primary-subclaim rule returns SC2 Γ for the precise age-defined causal claim. This is a bounded assessment of direct early-onset causal identification, not a refutation of the prospective association or the broader adiposity–colorectal-cancer causal literature. The cohort dose-response and genetic-natural-experiment equivalents were evaluated; their age/timing and system scopes do not silently become the exact registered outcome.",
  "limitations": "58 primary reports with 3 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}