{
  "completed": true,
  "status": "documented_historical_discovery_and_reconciliation",
  "provider": "Consensus",
  "provider_mode": "Historical browser/connector use as recorded in the source artifacts",
  "local_audit_date": "2026-10-09",
  "primary_comparison_count": null,
  "reported_usage": [],
  "grade_changed": false,
  "score_before": {
    "hsef_level": "Γ",
    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "Low",
    "confidence_rationale": "Framework: 'Low — Small number of studies; little independent replication; ... evidence primarily from a single lab or a closely connected set of labs', and confidence 'does NOT reflect whether the reviewer believes the hypothesis is correct.' SC1–SC3 meet the Low description (tendon and ligament efficacy from one connected programme, whose authors appear on 75% of PubMed-indexed BPC-157 records; one inconclusive independent tendon test; three uncontrolled human reports from one clinician-author; no human PK). SC4 is Moderate (positive rat gastrointestinal results from the originating programme and from two independent groups). The overall band follows the gating subclaims. Red-team change from High (RT-01), which had expressed certainty in the ceiling rather than evidence density.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "Systemic rat tendon and ligament experiments, rat gastrointestinal injury models (including two independent groups) and tendon-cell work establish biological plausibility and partial-system causal support, and cross Δ within the rat (SC5). The human literature contains a two-person IV administration report and local, uncontrolled symptom reports; the one controlled human trial was local and null-compatible. No controlled systemic structural-healing result exists in tendon, ligament or gut mucosa, so every gating subclaim is Γ."
  },
  "score_after": {
    "hsef_level": "Γ",
    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "Low",
    "confidence_rationale": "Framework: 'Low — Small number of studies; little independent replication; ... evidence primarily from a single lab or a closely connected set of labs', and confidence 'does NOT reflect whether the reviewer believes the hypothesis is correct.' SC1–SC3 meet the Low description (tendon and ligament efficacy from one connected programme, whose authors appear on 75% of PubMed-indexed BPC-157 records; one inconclusive independent tendon test; three uncontrolled human reports from one clinician-author; no human PK). SC4 is Moderate (positive rat gastrointestinal results from the originating programme and from two independent groups). The overall band follows the gating subclaims. Red-team change from High (RT-01), which had expressed certainty in the ceiling rather than evidence density.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "Systemic rat tendon and ligament experiments, rat gastrointestinal injury models (including two independent groups) and tendon-cell work establish biological plausibility and partial-system causal support, and cross Δ within the rat (SC5). The human literature contains a two-person IV administration report and local, uncontrolled symptom reports; the one controlled human trial was local and null-compatible. No controlled systemic structural-healing result exists in tendon, ligament or gut mucosa, so every gating subclaim is Γ."
  },
  "independent_blinded_audit": false,
  "raw_receipts": [
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\bpc-157-tissue-repair\\consensus-browser-links.json",
      "sha256": "b8f73ac516d69cbd34b135c76c2038785c30483260843fa066aee1e47311ddc7"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\bpc-157-tissue-repair\\consensus-browser.txt",
      "sha256": "6bc9a8add7dab81ec8c265f4bc557824984cc155af2ce4fc195e3c3842a4067c"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\bpc-157-tissue-repair\\consensus-pro-links.json",
      "sha256": "6a7285d9abb7a9a9ca0fb5a68e824cba0c36548db2aca7cf3453729d5d3186a1"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\bpc-157-tissue-repair\\consensus-pro.txt",
      "sha256": "328aa88339c89a7e82db7a1b5abccb9e78bf463840bbafe0e0d46f1fdc06cc16"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\bpc-157-tissue-repair\\consensus-targeted-check.txt",
      "sha256": "3cd3f29621cb9a5c6666f807c9bdef48681b277b6258603cd78510ce1723eab1"
    }
  ],
  "limitations": "This verifies documented historical use and links the record to the final edition. It adds no primary-source, full-text, independence or verification credit. Original access remains limited to the source-specific record.",
  "existing_primary_reconciliation": {
    "slug": "bpc-157-tissue-repair",
    "consensus_used": true,
    "rawproof": [
      "deliverables/prepublication-enrichment-2026-10-05/website-series/bpc-157-tissue-repair/consensus-browser.txt",
      "deliverables/prepublication-enrichment-2026-10-05/website-series/bpc-157-tissue-repair/consensus-targeted-check.txt",
      "deliverables/prepublication-enrichment-2026-10-05/website-series/bpc-157-tissue-repair/consensus-browser-links.json"
    ],
    "reconciliation_existing": "Yes; dated update lists 11 primary identifiers and Results/Methods check on rat/dog pharmacokinetics and material identity; human exposure not measured.",
    "primary_sources_matched": [
      "14554208",
      "15052688",
      "16583442",
      "20225319",
      "21030672",
      "29358856",
      "34324435",
      "36588717",
      "39325560",
      "40131143",
      "42542926"
    ],
    "limitations": "No inference from provider full-text claim to human efficacy; selected source-level checks only. No conversation thread IDs in link file."
  }
}