{
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  "provider_mode": "Historical browser/connector use as recorded in the source artifacts",
  "local_audit_date": "2026-10-09",
  "primary_comparison_count": null,
  "reported_usage": [],
  "grade_changed": false,
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    "hsef_level": "Γ",
    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "High",
    "confidence_rationale": "Confidence reflects evidence density and reproducibility, not belief that the model is false. The composite is bound by SC6, whose Γ placement rests on a dense, multi-laboratory, multi-design base: two opposing syntheses of 29-32 controlled-feeding studies, several large independent long-term RCTs (DIETFITS, POUNDS LOST, Foster 2010, DIOGENES) and a 53-trial meta-analysis, inpatient feeding trials plus an independent free-living replication, and proponents' own statement that rigorous research is still needed to compare the models. SC2-SC5 are individually Moderate (conflicting, single-group or analysis-dependent evidence). High does not mean glycemic load never matters.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "The endocrine link (carbohydrate/glycemic load → insulin and insulin-to-glucagon ratio) reaches Η on two independent causal lines. The downstream chain remains Γ: isocaloric fat-balance predictions are negative in short studies and untested at long duration; expenditure gains after adaptation are contested and lack a fat-loss correlate; GI effects on hunger, intake and regain are positive in defined contexts but insulin mediation failed its direct test; the responder rule failed its prespecified replication; and primacy has no necessity or rate-limitation evidence. Weakest-link, primary-subclaim and scope-matched aggregation all return Γ."
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    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "High",
    "confidence_rationale": "Confidence reflects evidence density and reproducibility, not belief that the model is false. The composite is bound by SC6, whose Γ placement rests on a dense, multi-laboratory, multi-design base: two opposing syntheses of 29-32 controlled-feeding studies, several large independent long-term RCTs (DIETFITS, POUNDS LOST, Foster 2010, DIOGENES) and a 53-trial meta-analysis, inpatient feeding trials plus an independent free-living replication, and proponents' own statement that rigorous research is still needed to compare the models. SC2-SC5 are individually Moderate (conflicting, single-group or analysis-dependent evidence). High does not mean glycemic load never matters.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "The endocrine link (carbohydrate/glycemic load → insulin and insulin-to-glucagon ratio) reaches Η on two independent causal lines. The downstream chain remains Γ: isocaloric fat-balance predictions are negative in short studies and untested at long duration; expenditure gains after adaptation are contested and lack a fat-loss correlate; GI effects on hunger, intake and regain are positive in defined contexts but insulin mediation failed its direct test; the responder rule failed its prespecified replication; and primacy has no necessity or rate-limitation evidence. Weakest-link, primary-subclaim and scope-matched aggregation all return Γ."
  },
  "independent_blinded_audit": false,
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  "limitations": "This verifies documented historical use and links the record to the final edition. It adds no primary-source, full-text, independence or verification credit. Original access remains limited to the source-specific record.",
  "existing_primary_reconciliation": {
    "slug": "carbohydrate-insulin-obesity",
    "consensus_used": true,
    "rawproof": [
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      "deliverables/prepublication-enrichment-2026-10-05/website-series/carbohydrate-insulin-obesity/consensus-browser-links.json"
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    "reconciliation_existing": "Yes; 8 primary identifiers matched to timeline; update explicitly says abstract-only from Consensus targeted answer and no independently readable body verified.",
    "primary_sources_matched": [
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    "limitations": "Abstract/metadata only; no full-text details attributed as independently verified. Secondary cohort analyses distinguished."
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