{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Creatine can preserve selected cognitive performance under experimental energetic stress; evidence for routine enhancement in rested healthy adults is inconsistent, and the brain mediator remains unisolated.",
  "implications": "The registered primary-subclaim rule selects SC2. Positive controlled cognitive effects in defined energetic-stress settings support Ε with Moderate confidence. Rested-adult and older-women nulls delimit generalization. Brain target engagement and muscle efficacy do not establish cognitive mediation, dementia prevention or routine enhancement across contexts. Weakest-link returns Γ; primary-subclaim and scope-matched return Ε.",
  "limitations": "61 primary reports with 5 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}