{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Prenatal conditions can alter adult disease risk, but the effect depends on the exposure, developmental window and later environment; low birthweight alone does not prove fetal nutritional programming.",
  "implications": "The registered primary SC3 yields Ε: defined prenatal exposures have human causal support, while internal and external negatives map limits to generalization. SC1 retains Β and controlled developmental SC2 retains Ε. This judgment uses an explicit closest-rubric adaptation because the literal aging-specific requirement is inapplicable to the developmental claim. The absence of a human deprivation RCT does not itself cap valid natural experiments; independence and specificity, rather than an observational label alone, block Ζ at the broad exposure class.",
  "limitations": "66 primary reports with 5 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}