{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Brain fluid transport is real and context dependent; its sleep-specific contribution to ordinary human neurodegeneration remains incompletely established.",
  "implications": "Overall Γ follows the registered SC3 clinical disease link, while narrow transport SC1–SC2 retain Ε under an explicit physiological rubric-fit adaptation. Mouse disease perturbations strengthen plausibility and mapped context, but artificial proteinopathy/injury and AQP4's multiple functions restrict human inference. Independent human clinical mediation remains uncrossed. This does not erase the causal transport results or the genuine contradictory measurements.",
  "limitations": "60 primary reports with 7 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}