{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "HIV is a well-supported causal antecedent of HIV-associated AIDS; infection does not guarantee progression, and other illnesses can cause similar immune deficiency.",
  "implications": "Overall Θ follows registered SC3. The convergent clinical causal case is strong and predictively consistent: documented acquisition precedes immune deterioration, suppression changes clinical trajectories, interrupted suppression worsens them, and prophylaxis prevents acquisition. Host and coinfection modifiers make infection insufficient for inevitable disease. Non-HIV ICL shows that low CD4/OI phenotypes are not HIV-specific; its existence does not erase the viral causal process established by intervention, but it blocks a broader claim that HIV is necessary for all acquired immunodeficiency.",
  "limitations": "63 primary reports with 3 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}