{
  "completed": true,
  "status": "documented_historical_discovery_and_reconciliation",
  "provider": "Consensus",
  "provider_mode": "Historical browser/connector use as recorded in the source artifacts",
  "local_audit_date": "2026-10-09",
  "primary_comparison_count": null,
  "reported_usage": [],
  "grade_changed": false,
  "score_before": {
    "hsef_level": "Θ",
    "hsef_descriptor": "High predictive accuracy, minimal unresolved exceptions",
    "confidence": "High",
    "confidence_rationale": "The core direction is replicated across prospective cohorts, two prophylactic vaccine platforms, national invasive-cancer programmes, randomized screening, multi-target tumour assays, morphology-first pathology, genomics, and E6/E7 loss-of-function systems. Confidence is High in the near-necessity of persistent carcinogenic HPV for the common pathway and lower only for exception-free wording and continued human tumour dependence.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "Persistent carcinogenic HPV is the primary upstream cause of nearly all common squamous and usual-type cervical carcinomas, and preventing infection changes high-grade and invasive disease as predicted. The claim stops at Θ because 'HPV-associated' is circular unless independently operationalized, most infections are not sufficient, and rare HPV-independent squamous and glandular cervical carcinomas are real."
  },
  "score_after": {
    "hsef_level": "Θ",
    "hsef_descriptor": "High predictive accuracy, minimal unresolved exceptions",
    "confidence": "High",
    "confidence_rationale": "The core direction is replicated across prospective cohorts, two prophylactic vaccine platforms, national invasive-cancer programmes, randomized screening, multi-target tumour assays, morphology-first pathology, genomics, and E6/E7 loss-of-function systems. Confidence is High in the near-necessity of persistent carcinogenic HPV for the common pathway and lower only for exception-free wording and continued human tumour dependence.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "Persistent carcinogenic HPV is the primary upstream cause of nearly all common squamous and usual-type cervical carcinomas, and preventing infection changes high-grade and invasive disease as predicted. The claim stops at Θ because 'HPV-associated' is circular unless independently operationalized, most infections are not sufficient, and rare HPV-independent squamous and glandular cervical carcinomas are real."
  },
  "independent_blinded_audit": false,
  "raw_receipts": [
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\hpv-cervical-carcinoma\\consensus-browser-links.json",
      "sha256": "ab99ec5e84d2fd06378fa52fa9f9c9d12e6f46eee7aaa27467dfe26978160b99"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\hpv-cervical-carcinoma\\consensus-browser.txt",
      "sha256": "c75b4bf8ccc8e055854f52ca0b5e88bb76026a4eb61148e649ab2708100f9123"
    },
    {
      "path": "deliverables\\prepublication-enrichment-2026-10-05\\website-series\\hpv-cervical-carcinoma\\consensus-targeted-check.txt",
      "sha256": "dc9dc4827ca81560d65164ff1c1bc026c0749d2ec6766e58786cb0578d861fa7"
    }
  ],
  "limitations": "This verifies documented historical use and links the record to the final edition. It adds no primary-source, full-text, independence or verification credit. Original access remains limited to the source-specific record.",
  "existing_primary_reconciliation": {
    "slug": "hpv-cervical-carcinoma",
    "consensus_used": true,
    "rawproof": [
      "deliverables/prepublication-enrichment-2026-10-05/website-series/hpv-cervical-carcinoma/consensus-browser.txt",
      "deliverables/prepublication-enrichment-2026-10-05/website-series/hpv-cervical-carcinoma/consensus-targeted-check.txt",
      "deliverables/prepublication-enrichment-2026-10-05/website-series/hpv-cervical-carcinoma/consensus-browser-links.json"
    ],
    "reconciliation_existing": "Yes; 9 primary identifiers matched; update says abstract/metadata checked and notes broad response irrelevance plus focused follow-up retrieval gaps.",
    "primary_sources_matched": [
      "10451482",
      "17494925",
      "19435895",
      "21900119",
      "25100830",
      "32997908",
      "34741816",
      "37702216",
      "40347270"
    ],
    "limitations": "No independently readable body for Consensus-reported full-text details; initial broad response had irrelevant records."
  }
}