{ "completed": true, "status": "completed_original_source_reconciliation", "provider_mode": "Consensus Pro signed-in browser; observed output and citation link mappings", "queries": [ "https://consensus.app/search/oral-magnesium-effects-sleep/UIuYDhmHQv2mJ_Q4YU-JMw/" ], "query_record_note": "Exact visible question/response retained privately in raw browser receipt.", "primary_comparison_count": 11, "primary_comparisons": [ { "pmid": "40918053", "doi": "10.2147/NSS.S524348", "source_type": "primary study report", "study_group": "MG-BISGLYCINATE-DRKS00031494", "access_depth": "full_text_partial", "consensus_aspect": "Consensus describes a modest bisglycinate effect and1523mg glycine coingredient.", "result_comparison": "Selected original Methods confirm the studied bisglycinate salt supplies250mgMgand1523mgglycine daily; this is ligand exposure, not necessarily separately added freeglycine. Original Results show small primaryISI benefit,d=.2,p=.049,153baselineanalyzed and134completed. There is no ligand-matched control, objective sleep or established clinically important between-arm responder result.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/40918053/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\40918053-s1-p0-4-12-14-15-17.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\40918053-s2-p0-8-10-13-16-18.json" ] }, { "pmid": "21199787", "doi": "10.1684/mrh.2010.0220", "source_type": "primary study report", "study_group": "PMID21199787", "access_depth": "abstract_metadata", "consensus_aspect": "Consensus reports equal globalPSQI improvements with citrate andplacebo but suggests deficient responders.", "result_comparison": "Original abstract confirms no supplement-specific globalPSQI effect. Low-status serum andCRP responses occur in selected baseline groups, yet they do not establish sleep responsiveness or a deficiency-only causal boundary.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/21199787/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [] }, { "pmid": "23853635", "doi": "", "source_type": "primary study report", "study_group": "PMID23853635", "access_depth": "full_text_partial", "consensus_aspect": "Provider emphasizes subjective improvements and low nutritional status in the older-adult trial.", "result_comparison": "Selected original Methods show dietaryMg<75%RDA andserumMg<0.95mmol/L; this does not prove every participant had clinical hypomagnesemia. Sample power usedrenin;46entered and43completed. Selected Results retain total-sleep-time null alongside positiveISI/log/hormone measures.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/23853635/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\23853635-s1-p0-1.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\23853635-s2-p0-3-5.json" ] }, { "pmid": "39252819", "doi": "10.1016/j.sleepx.2024.100121", "source_type": "primary study report", "study_group": "MG-THREONATE-ISRCTN14728094", "access_depth": "full_text_partial", "consensus_aspect": "Provider mentions selected wearable and awakening benefits but understates prespecification limits.", "result_comparison": "Original body has null overallISI time×group(p=.39) and severalLSEQsleep subscales. Correction40567408 adds retrospective-registration and competing-interest disclosures, attached to the parent rather than counted as anotherstudy. Wearable scores are not directpolysomnographic architecture.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/39252819/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\39252819-s1-p0-6-7-14-32.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\39252819-s11-p0.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\39252819-s2-p3-7-15.json" ] }, { "pmid": "41601871", "doi": "10.3389/fnut.2025.1729164", "source_type": "primary study report", "study_group": "MG-THREONATE-ACTRN12624000379516", "access_depth": "full_text_partial", "consensus_aspect": "Consensus synthesis does not fully detail the newer threonate endpoint nulls.", "result_comparison": "Selected original body confirms prospective registration and allocation-guess assessment; sleep-related-impairment improves, while sleepdisturbance, restorative sleep andallring-derivedsleep outcomes are null. The severe subgroup is exploratory. Cognitive-age transformation is not observed brainrejuvenation.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/41601871/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-10-20-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\41601871-s1-p0.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\41601871-s2-p20-29-30-32-39.json" ] }, { "pmid": "39534260", "doi": "10.3389/fendo.2024.1370733", "source_type": "primary study report", "study_group": "MG-K-INSOMNIA-NCT04642313", "access_depth": "full_text_partial", "consensus_aspect": "Provider general sleep narrative could obscure trial-specific baseline comparability.", "result_comparison": "Selected original Results report baselineISI category imbalancep=.0001, with post-treatment between-group association also p=.0001. Without an adjusted change contrast this is a weaker causal anchor; selected Methods also impose a Mg/K-restricted diet. The two metabolic/renal followups share the same trial.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/39534260/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\39534260-s1-p0-13.json", "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\39534260-s2-p0-1-2.json" ] }, { "pmid": "30562392", "doi": "10.1371/journal.pone.0208454", "source_type": "primary study report", "study_group": "MG-B6-EUDRACT2015-003749-24", "access_depth": "abstract_metadata", "consensus_aspect": "Consensus sometimes treats stress improvement withMg as isolated nutrient efficacy.", "result_comparison": "Original randomization comparesMg+B6toMg, with noMg-free arm. The overall primary comparison is null; severe-stress subgroup advantage concerns addedB6. Improvements within botharms do not identify Mgcausality.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/30562392/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-10-20-6000.json" ], "body_receipts": [] }, { "pmid": "31330811", "doi": "10.3390/nu11071663", "source_type": "primary study report", "study_group": "PMID31330811", "access_depth": "full_text_partial", "consensus_aspect": "Provider correctly separates form absorption from direct sleepcomparisons.", "result_comparison": "Original body confirms serum-profile differences alongside null urinary contrasts and unequal elemental doses across formulations. These findings measure availability, not superiority ofglycinate/threonate for sleep.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/31330811/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-20-30-6000.json" ], "body_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\body-presentation-receipts\\31330811-s2-p9-12-13-15-17.json" ] }, { "pmid": "8232845", "doi": "10.1159/000118988", "source_type": "primary study report", "study_group": "PMID8232845", "access_depth": "abstract_metadata", "consensus_aspect": "Provider attributes plausibility to deficiency/neural models.", "result_comparison": "Original rat experiment shows longdeficiency sleep disruption and restoration onMg repletion. Its restricted nutritional/species context cannot establish a broad hypnotic effect inreplete adults.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/8232845/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-0-10-6000.json" ], "body_receipts": [] }, { "pmid": "34092248", "doi": "10.1186/s12986-021-00586-9", "source_type": "primary study report", "study_group": "PMID34092248", "access_depth": "abstract_metadata", "consensus_aspect": "Provider discusses multiingredient contamination ofsleep results.", "result_comparison": "Original factorialPCOS trial reportsPSQI improvements inmelatonin andmelatonin+Mg groups, not a demonstratedMg-only advantage. Component attribution mustretainthe actualarms ratherthantransfer the combinedresult.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/34092248/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-20-30-6000.json" ], "body_receipts": [] }, { "pmid": "37520407", "doi": "10.2147/BCTT.S413435", "source_type": "primary study report", "study_group": "PMID37520407", "access_depth": "abstract_metadata", "consensus_aspect": "Completeness of the provider formulation outline", "result_comparison": "The original2023 trial randomized109 postoperative breast-cancer patients and found no between-arm PSQI, mood or cognitive benefit. It supplies a relevant null formulation result omitted from the provider outline. Enrollment was for pain prevention, so it cannot be treated as a direct falsification of the registered primary-insomnia claim. Search omissions and limited coverage do not establish literature-wide absence.", "original_source": "https://pubmed.ncbi.nlm.nih.gov/37520407/", "source_examination_receipts": [ "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\examinations\\original-58-59-6000.json" ], "body_receipts": [] } ], "grade_changed": false, "grade_change_note": "Source-based adjudication; no independent blinded regrade claimed.", "raw_receipts": [ { "path": "deliverables\\hsef_v53_traffic_first_five_2026-10-12\\magnesium-sleep\\consensus-browser-2026-10-12.json", "sha256": "f6de31a86abb6d2d56781dde9c59c9840f6a633b2f5f100723cd2f82a5f589e6" } ], "independent_blinded_audit": false, "cutoff": "2026-10-12", "completed_utc": "2026-10-13T06:25:02.142837+00:00", "conclusion": "Endpoint hierarchy, experimental scope and original-source limits determine the evidence cards; provider wording does not override them." }