{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Particles are detected in cardiovascular samples and associate with events; their causal contribution at real-world human exposure and the clinical benefit of detox remain unresolved.",
  "implications": "The preregistered primary-subclaim rule returns Γ from the human particle-event SC2. Fifty-nine original reports include analytical studies, experimental injury, human observational outcomes and distinct PFAS kinetics/removal. Experimental plausibility and prospective association do not yet establish the exposure-specific human cardiovascular dependency. Genuine detection and genuine PFAS burden reduction are retained without converting them to demonstrated clinical harm or detox benefit.",
  "limitations": "59 primary reports with 2 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}