{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used complete abstracts/status records and selected original partial-body passages. No complete-paper audit or independent scientific peer review is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Scope-matched SC5 gives Γ. Endogenous mitochondrial lesions demonstrate convergent model causality (SC2 Ζ), and HD biogenesis has contextual contribution (SC3 Ε). Neither set identifies age-related respiratory failure as the spontaneous upstream cause across disease classes. The registered phrase sporadic Huntington disease is scientifically ill-posed: the examined HTT disease is genetically initiated, and is retained as an explicit counterexample rather than silently recast.",
  "implications": "Scope-matched SC5 gives Γ. Endogenous mitochondrial lesions demonstrate convergent model causality (SC2 Ζ), and HD biogenesis has contextual contribution (SC3 Ε). Neither set identifies age-related respiratory failure as the spontaneous upstream cause across disease classes. The registered phrase sporadic Huntington disease is scientifically ill-posed: the examined HTT disease is genetically initiated, and is retained as an explicit counterexample rather than silently recast.",
  "limitations": "70 primary reports with 6 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}