{
  "completed": true,
  "status": "documented_historical_discovery_and_reconciliation",
  "provider": "Consensus",
  "provider_mode": "Historical browser/connector use as recorded in the source artifacts",
  "local_audit_date": "2026-10-09",
  "primary_comparison_count": null,
  "reported_usage": [],
  "grade_changed": false,
  "score_before": {
    "hsef_level": "Γ",
    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "Moderate",
    "confidence_rationale": "66 primary reports with 9 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "The weakest-link conjunction returns Γ. Physiological host substrate can be recruited after imposed seeds, and source-restricted transfer and receptor perturbations demonstrate substantial capabilities. Selective blockade of spontaneous propagation has not established progression necessity in both disease families. Canonical PrP loss/rescue is stronger comparator evidence and is not transferred to the nominal tau/alpha-synuclein claim. Host state, compartment and intracellular toxicity constrain a universal spread-driven account."
  },
  "score_after": {
    "hsef_level": "Γ",
    "hsef_descriptor": "Mechanistically plausible, partial system support",
    "confidence": "Moderate",
    "confidence_rationale": "66 primary reports with 9 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness.",
    "rests_on_non_peer_reviewed_work": false,
    "rationale": "The weakest-link conjunction returns Γ. Physiological host substrate can be recruited after imposed seeds, and source-restricted transfer and receptor perturbations demonstrate substantial capabilities. Selective blockade of spontaneous propagation has not established progression necessity in both disease families. Canonical PrP loss/rescue is stronger comparator evidence and is not transferred to the nominal tau/alpha-synuclein claim. Host state, compartment and intracellular toxicity constrain a universal spread-driven account."
  },
  "independent_blinded_audit": false,
  "raw_receipts": [
    {
      "path": "deliverables\\hsef_v53_popularity_ranks_21_25_2026-10-06\\prion-like-protein-spread\\consensus\\broad-browser-snapshot.txt",
      "sha256": "e8c673f378c38e15e71f5ddf308cfefb97c4aef89ec542a5d966662a7ea03f05"
    },
    {
      "path": "deliverables\\hsef_v53_popularity_ranks_21_25_2026-10-06\\prion-like-protein-spread\\consensus\\query-ledger.json",
      "sha256": "c36b161879b3daad6d7671e80686231ca603436e87c6ce8c84df6fc63bdbd37d"
    },
    {
      "path": "deliverables\\hsef_v53_popularity_ranks_21_25_2026-10-06\\prion-like-protein-spread\\consensus\\reconciliation.md",
      "sha256": "a318991dd1e99f3afbac73c5341f292ec2aff663c95418864fc45c51ecd1ca28"
    },
    {
      "path": "deliverables\\hsef_v53_popularity_ranks_21_25_2026-10-06\\prion-like-protein-spread\\consensus\\targeted-browser-snapshot.txt",
      "sha256": "e040615b9bc52b71008ebd5606c4a15f1b6764c9dff08d78fccf7594dac9b154"
    }
  ],
  "limitations": "This verifies documented historical use and links the record to the final edition. It adds no primary-source, full-text, independence or verification credit. Original access remains limited to the source-specific record."
}