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  "completed": true,
  "status": "completed_original_source_reconciliation",
  "provider_mode": "Consensus Pro signed-in browser; observed output and citation link mappings",
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    "https://consensus.app/search/dietary-protein-effects-older-adults/DudKItpNSg-OZEBY4542Zw/"
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  "query_record_note": "Exact visible question/response retained privately in raw browser receipt.",
  "primary_comparison_count": 10,
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    {
      "pmid": "33564844",
      "doi": "10.1093/ajcn/nqaa372",
      "source_type": "primary study report",
      "study_group": "PMID33564844",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus states that supplied CALM evidence concerns cognitive-training abstracts and gives no usable protein results.",
      "result_comparison": "The examined original 2021 nutrition trial has 208 older adults randomized to carbohydrate, collagen, whey, light training plus whey, or heavy training plus whey for one year. Protein-only arms are null; loading contrasts are positive. This is a retrieval identity error, not missing literature, and no training-only arm proves whey synergy.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/33564844/",
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    {
      "pmid": "22889730",
      "doi": "10.1016/j.jamda.2012.07.005",
      "source_type": "primary study report",
      "study_group": "Tieland_nutritiononly_NCT01109628",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus retrieves Tieland training but omits the requested nutrition-only trial.",
      "result_comparison": "The separate original 65-person nutrition-only trial reports a positive SPPB interaction without lean-mass gain; leg-extension strength is only a trend. This positive functional result prevents an unqualified no-benefit summary. Exact achieved total protein remains unverified at our abstract access depth.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/22889730/",
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    {
      "pmid": "22770932",
      "doi": "10.1016/j.jamda.2012.05.020",
      "source_type": "primary study report",
      "study_group": "Tieland_training_NCT01110369",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus correctly describes 62 frail adults with matched training and protein-associated lean-mass gain but no added strength or SPPB effect.",
      "result_comparison": "Original abstract agrees. It is NCT01110369, separate from the 65-person nutrition-only NCT01109628 study. Their endpoint difference does not represent duplicate reporting or contradictory measurements in the same cohort.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/22770932/",
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    {
      "pmid": "26170041",
      "doi": "10.1016/j.jamda.2015.05.021",
      "source_type": "primary study report",
      "study_group": "PROVIDE_NTR2323",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus says PROVIDE primary grip and SPPB results are null, with secondary chair-rise and appendicular mass benefits.",
      "result_comparison": "Original abstract agrees with this endpoint hierarchy. Vitamin D, leucine, whey and other nutrients are bundled; the benefit cannot be assigned to protein quantity alone or described as a positive primary functional trial.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/26170041/",
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    {
      "pmid": "29532075",
      "doi": "10.1001/jamainternmed.2018.0008",
      "source_type": "primary study report",
      "study_group": "PMID29532075",
      "access_depth": "full_text_partial",
      "consensus_aspect": "Consensus identifies the controlled 0.8 versus 1.3 g/kg/day functional null and factorial testosterone design.",
      "result_comparison": "Original selected PMC Methods/Results confirms controlled energy, intake checks and separately analyzed outcomes. This strong null in its baseline-defined group is retained without generalizing to every malnourished or frail older adult.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/29532075/",
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    {
      "pmid": "25646324",
      "doi": "10.3945/ajcn.114.090290",
      "source_type": "primary study report",
      "study_group": "PMID25646324",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus lacks the original 2015 weight-loss trial and passes along review-level suggestions of mass and function benefit.",
      "result_comparison": "Original abstract verifies 80 participants, matched resistance training, actual intake 1.11 versus 0.85 g/kg/day, and preserved appendicular lean mass. Strength and physical function improve over time without between-arm differences; review-level language cannot replace that functional null.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/25646324/",
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    {
      "pmid": "30475969",
      "doi": "10.1093/ajcn/nqy214",
      "source_type": "primary study report",
      "study_group": "PMID30475969",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus headline says higher protein usually does not improve strength or overall function and does not recover Park2018.",
      "result_comparison": "Original 120-person randomized trial in malnourished prefrail/frail elders directly compares 0.8, 1.2 and 1.5 g/kg/day: highest-dose mass and secondary gait improvement are positive, intermediate-dose outcomes null. The scoped clinical positive is retained while rejecting a universal dose rule.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/30475969/",
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    {
      "pmid": "28166780",
      "doi": "10.1186/s12937-017-0229-6",
      "source_type": "primary study report",
      "study_group": "PMID28166780",
      "access_depth": "full_text_partial",
      "consensus_aspect": "Consensus identifies achieved intake reporting as a gap but does not recover this original factorial detail.",
      "result_comparison": "Original Methods/Results shows prescribed targets differ from achieved intake, no fat-free-mass protein main or interaction effect, and selected grip/gait interactions. Secondary interactions and positive within-arm changes are not interchangeable with a general protein effect.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/28166780/",
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    {
      "pmid": "32162241",
      "doi": "10.1007/s40520-020-01519-x",
      "source_type": "primary study report",
      "study_group": "PROVIDE_NTR2323",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus repeats PROVIDE-related supplement and tolerability evidence alongside clinical outcomes.",
      "result_comparison": "Original abstract identifies the same 380-person RCT plus voluntary open-label extension. It informs product-specific tolerability over six months, not a new independent causal efficacy line or universal renal safety.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/32162241/",
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    {
      "pmid": "32471657",
      "doi": "10.1016/j.jamda.2020.03.030",
      "source_type": "primary study report",
      "study_group": "OPEN_NCT02702037",
      "access_depth": "abstract_metadata",
      "consensus_aspect": "Consensus notes reporting and context gaps but does not detail postrandomization adherence selection.",
      "result_comparison": "Original OPEN abstract has a null main function result, with body-weight and high-adherence subgroup signals. Adherence after allocation cannot define a preregistered beneficiary group; caregiver-time reanalysis is the same trial.",
      "original_source": "https://pubmed.ncbi.nlm.nih.gov/32471657/",
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  "grade_changed": false,
  "grade_change_note": "Source-based adjudication; no independent blinded regrade claimed.",
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  "independent_blinded_audit": false,
  "cutoff": "2026-10-12",
  "completed_utc": "2026-10-13T06:25:03.588422+00:00",
  "conclusion": "Endpoint hierarchy, experimental scope and original-source limits determine the evidence cards; provider wording does not override them."
}
