{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used complete abstracts/status records and selected original partial-body passages. No complete-paper audit or independent scientific peer review is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Some infections can affect the brain, and microbial material can be detected in tissue. This review asks the different question of whether healthy brain tissue normally contains a living resident microbial community that drives neurodegeneration.",
  "implications": "Preregistered primary-subclaim aggregation returns Α because SC1 living-human community existence remains unresolved under the low-biomass contamination gate. SC2 Β and SC3 Γ do not replace that prerequisite. Weakest-link and scope-matched sensitivities also return Α. Positive fish ecology and AD autopsy culture are explicitly retained rather than dismissed.",
  "limitations": "59 primary reports with 9 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}