Cutoff: 13 October 2026. Consensus supports discovery and checks of specific source aspects; it is not a primary study, a full-paper audit or a causal probability meter.
Actual original Methods/Results show that the detailed longitudinal cohort comprised2355people exposed for at least one year, full randomized raw data were not recovered, and the adjusted cholesterol-death association pooled both arms with no detected cholesterol-by-arm interaction. This is observational mediator covariance, not randomized proof that cholesterol lowering causes death. The broader9423cohort's mortality graphs and the149partially recovered autopsies are separate evidence components. Original PMID27071971. Access: full_text_partial.
Actual selected original Results give all-causeP=.051, a borderline result rounded in the abstract; coronary and cardiovascular mortality contrasts were significant. The458men, median39-month horizon and highLA safflower-oil/margarine intervention are verified, while usual-modern-oil toxicity and an inflammatory mediator are not demonstrated. Original PMID23386268. Access: full_text_partial.
The original1989trial abstract agrees for overall cardiovascular events and mortality. It also reports a mean dietary exposure of384days despite the longer trial, and the institutional food replacement changed several lipid-related features. The1989and2016reports belong to one parent trial; the recovered report's meta-analysis does not count as an additional original clinical experiment. Original PMID2643423. Access: abstract_metadata.
The actual Finnish abstract describes one hospital on the diet, the other as control, then reversal after six years. Despite anRCTmetadata tag, this is treated as a controlled hospital-period natural experiment, with the male favourable result retained and the women's nonsignificant report grouped under the same parent programme. Original PMID393644. Access: abstract_metadata.
The originalDIVAStrial confirms16-week isoenergetic replacement and lower LDLbut a null primary flow-mediated-dilatation endpoint. Its17-20%mortality reduction was estimated from lipid change, not observed. This source supports experimental lipid response, not a coronary-event crossing. Original PMID26016869. Access: abstract_metadata.
The original67-person randomized isocaloric trial found lower liver fat and selected inflammatory signals with vegetableomega6versus butter and no reported oxidative-stress or proinflammatory signal. Some lipid findings were restricted to postrandomization compliant participants. Short markers cannot prove universal safety or long-term event protection, but the unfavourable-inflammation prediction did not hold in this experiment. Original PMID22492369. Access: abstract_metadata.
Actual original Methods confirm recruitment through existing carnivore social-media communities and at least six months of diet maintenance, with self-reported measurements and no balanced-diet control. Selected Results retain perceived benefits, improved glycemic reports and high LDLwithout converting these into adjudicated long-term cardiovascular superiority. Original PMID34934897. Access: full_text_partial.
The originalLyonallocated programme lowered coronary events while LAintake decreased and ALA/oleic exposure increased, with similar serum lipids. It is a positive whole-pattern result and does not prove LAharm. More generally, our registered claim is LA-rich oils, not pureLA, so anALA-containing oil is not excluded merely for containingALA. Original PMID7911176. Access: abstract_metadata.
The examined originalMRreports favourable linoleic-CAD estimates using allele scores and pleiotropy-robust summary methods. It is retained as causal-inference support, while the exposure is lifelong circulating metabolism rather than assigned isocaloric oil replacement. It does not independently verify the clinical dietary bridge. Original PMID33924952. Access: abstract_metadata.
The originallargePUFAGWAS/MRreport found inconsistent linoleic estimates across methods and endpoints and important LDL/FADSlocus sensitivity. Those assumptions and shared metabolic pathways are examined rather than treating everyMRpaper as either simple association or independently convergent proof. Original PMID35692035. Access: abstract_metadata.
FADSDIETprovides a relevant qualification: short CRPand fatty-acid responses differed byFADS1genotype among62men receiving enrichment. There was no randomized saturated-fat comparator and no clinical coronary inflammatory endpoint. The result narrows a universal no-marker-response claim without establishing usual-intake clinical harm. Original PMID30624587. Access: abstract_metadata.
The originalDanishcase-cohort study found no adiposeLAassociation with infarction after16years or shorter horizons. That null is retained alongside favourableCHSandEPICNorfolkassociations, preventing selective citation of only positive or adverse cohorts. Original PMID33687534. Access: abstract_metadata.
The originalDutch20,069-person study found no coronary incidence association across LAintake differences mainly replacing carbohydrate. It is not a randomized saturated-fat replacement trial, so its null cannot directly refute the registered oil-swap proposition. Original PMID21816117. Access: abstract_metadata.
Consensus was used to identify literature and cross-check specific claims about design, endpoints, scope and research gaps. Those aspects were checked against original primary abstracts/status records and selected original Methods/Results passages. Consensus output was not treated as original full text. Provider search omissions are not evidence that a study does not exist. Source access and examination receipts are retained. Scite use or monthly unavailability is recorded per case; provider citation counts do not change causal grades.