{
  "slug": "saturated-fat-linoleic-coronary",
  "round": 2,
  "date": "2026-10-14",
  "authoring_model": "Sol 6.1",
  "adversarial_reviewer": "Claude Opus 5.5 (Anthropic)",
  "canonical": "hsef_v53_traffic_ranks_11_15_2026-10-13\\saturated-fat-linoleic-coronary\\saturated-fat-linoleic-coronary.review.md",
  "level_before": "Γ",
  "level_after": "Γ",
  "confidence_before": "Moderate",
  "confidence_after": "Moderate",
  "role_before": "epiphenomenon",
  "role_after": "epiphenomenon",
  "counts": {
    "critical": 0,
    "major": 0,
    "minor": 1,
    "editorial": 4
  },
  "pmids_checked": 60,
  "pmids_failed": 0,
  "dois_checked": 60,
  "dois_failed": 0,
  "retractions_or_eoc": 0,
  "claims_spot_checked": 15,
  "claims_unsupported": 0,
  "findings": [
    {
      "id": "A1",
      "severity": "Editorial",
      "location": "throughout (144 lines)",
      "original": "lost inter-word spaces, e.g. \"LDLcholesterol\", \"was384days\", \"The195-person16-week\", \"UKBiobank\"",
      "corrected": "\"LDL cholesterol\", \"was 384 days\", \"The 195-person 16-week\", \"UK Biobank\"",
      "evidence": "known upstream builder whitespace defect; repair inserts whitespace only (whitespace-stripped file identical to original apart from A4)"
    },
    {
      "id": "A2",
      "severity": "Editorial",
      "location": "evidence cards [2], [5], [43]",
      "original": "ErratumIn: PMIDnot supplied.",
      "corrected": "ErratumIn: PMID not supplied.",
      "evidence": "same builder defect; erratum identifiers genuinely absent from retrieved metadata"
    },
    {
      "id": "A3",
      "severity": "Editorial",
      "location": "REFERENCES 9, 10, 45, 48",
      "original": "DOI: .",
      "corrected": "DOI: not indexed in PubMed.",
      "evidence": "PubMed holds no DOI for PMID 1484945, 1431574, 16483027, 5900208"
    },
    {
      "id": "A4",
      "severity": "Editorial",
      "location": "evidence cards [10], [23]",
      "original": "lipoproteina",
      "corrected": "lipoprotein[a]",
      "evidence": "source titles: \"serum lipoprotein[a] levels\" (PMID 1431574); \"serum lipoprotein(a) concentration\" (PMID 38714425)"
    },
    {
      "id": "A5",
      "severity": "Minor",
      "location": "scorecard final_score.confidence_rationale",
      "original": "density, heterogeneous controls and incomplete access set the confidence, not correctness",
      "corrected": "rationale resting on evidence density and reproducibility alone, with access depth reported separately",
      "evidence": "the framework ties confidence to evidence density and reproducibility, not the reviewer's access depth; re-derived on legitimate grounds the band remains Moderate, so only the basis changed",
      "lead_policy_2026_10_14": "two-step test applied: access depth struck as a determinant, band re-derived from what remained; step 2 keeps Moderate because the review documents substantive evidence-quality and reproducibility concerns (the accessible allocated trials conflict outright (Minnesota null, Sydney adverse, the Finnish hospital periods favourable) and the cohort and genetic estimates disagree with each other), which are legitimate determinants, and the High band's requirement of extensive independent replication across labs, models and assay modalities is not met"
    }
  ],
  "rejected_findings": [
    "aggregation: primary-subclaim rule preregistered with primary SC2; scope-matched coincides at Γ; SC4 Α correctly reported as a narrower sensitivity",
    "Β/Γ boundary: controlled isoenergetic feeding gives partial system support; no intervention moves the registered clinical endpoint",
    "causal role epiphenomenon correctly derived at framework Step 2 and scoped to the proposed benefit account",
    "momentum 'Mechanistic only' correct; no pending allocated oil-swap coronary-event trial named",
    "no consortium first authors, so the dropped-collective-author bug does not occur",
    "Finnish Mental Hospital Study downgraded from PubMed RCT tag to hospital-period natural experiment: defensible reading, stated in the review",
    "PubMed title field for reference 36 drops italicised gene name: standing convention",
    "print/issue vs e-pub year differences within the accepted +/-1",
    "renderer defect printing the nominal as its own 'Best-supported rival': checked, absent (models_evaluated[0] is rank 1, is_nominal false; nominal is rank 4)",
    "spliced-provenance artifacts (false earlier-approval clause, reviewer-notes contradiction): checked, absent - this package has no consensus-consistency block"
  ],
  "residual_limitations": [
    "erratum identifiers for references 2, 5 and 43 unresolved in retrieved metadata",
    "three sources at partial-body depth, 57 at bounded abstract/status depth; full-text-derived figures checked against package retrieval receipts",
    "scorecard provenance strings name the generating system 'Codex'; not altered here"
  ],
  "scorecard_changed": true,
  "validator": {
    "tool": "hsef-hypothesis-review-v5/tools/validate_review.py",
    "pass": 32,
    "warn": 0,
    "fail": 1,
    "fail_checks": [
      "v5.lay_summary"
    ],
    "note": "v5.lay_summary is marked by the validator as mandatory from v5.4 and does not apply to this v5.3 package; all v5.3 checks pass"
  },
  "status": "Approved as revised",
  "scorecard_fields_changed": [
    "final_score.confidence_rationale"
  ]
}