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    "rationale": "The central claim is a population-level causal-initiation claim, carried by SC1 at Theta. Under the prescribed scope-matched rule the overall equals SC1 (Theta); primary-subclaim agrees, and weakest-link would return Zeta only because the mechanistic subclaim SC3 is deliberately held at Zeta for partial co-dependence of its human molecular lines. Theta is warranted: exposure-response across independent populations, incidence decline after cessation, a dose-scaled carcinogen mutational signature in tumours, and animal carcinogenicity converge, each excluding a different confounder, and the framework and cancer rubric name this exposure-carcinoma pair as a top-of-ladder calibration case. Omega is blocked because smoking is neither necessary (never-smoker cancers, EGFR-mutant subset) nor sufficient (most smokers never develop lung cancer)."
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