{
  "title": "What this review means",
  "includeSubclaimIllustrations": false,
  "redteamReviewed": true,
  "accessNotice": "Source checking used bounded original primary abstract passages/status records and selected original partial-body passages. No complete-abstract or complete-paper audit, or independent scientific peer review, is claimed. Detailed access counts and limitations appear in the review.",
  "overview": "Super-enhancer labels identify many important regulatory regions, but native perturbations favor heterogeneous local grammar over a uniquely distinct cell-identity control class.",
  "implications": "The registered weakest-link returns Β from SC1 and SC2. SC1 is a reproducible operational association, not evidence for qualitative causal class distinction. SC2 has local mechanistic plausibility at Γ, but one native class-distinction prediction challenge lowers it to Β: called clusters can be dispensable while conventional elements are strongly required, and additive/hierarchical or facilitator rules explain many effects. Native nonadditivity is retained and a universal additive counterclaim is rejected. SC3 is Γ for the prespecified distinct-class disproportionate identity claim, while individual native lineage dependencies have real context-specific causality.",
  "limitations": "66 primary reports with 12 selected partial-body examinations; density, heterogeneous controls and incomplete access set the confidence, not correctness. The grade applies to the exact registered claim; stronger findings for narrower subclaims remain separate. No complete-paper audit or blinded calibration is claimed. This educational review does not establish an individual treatment recommendation."
}