{
 "slug": "two-hit-vascular-dementia",
 "round": 2,
 "date": "2026-10-14",
 "authoring_model": "Sol 6.1",
 "adversarial_reviewer": "Claude Opus 5.5 (Anthropic)",
 "canonical_path": "consensus_consistency_audit_2026-10-09/revised/two-hit-vascular-dementia/two-hit-vascular-dementia.review.md",
 "level_before": "Γ",
 "level_after": "Γ",
 "confidence_before": "Moderate",
 "confidence_after": "Moderate",
 "role_before": "reinforcing / stabilizing factor",
 "role_after": "reinforcing / stabilizing factor",
 "counts": {
  "critical": 0,
  "major": 1,
  "minor": 1,
  "editorial": 0
 },
 "pmids_checked": 69,
 "pmids_failed": 0,
 "retraction_flags_in_references": 0,
 "retracted_exclusions_confirmed": [
  "24336108",
  "29400711"
 ],
 "claims_spot_checked": 12,
 "collective_author_bug_present": true,
 "validator": {
  "stored_report_v2_3_ok": true,
  "rerun_with_bundled_v5_4": "1 FAIL (v5.lay_summary, v5.4-only) + 1 WARN (v5.claim_form, rejected by convention), 32 pass",
  "output": "validator.txt"
 },
 "findings": [
  {
   "id": 1,
   "severity": "Major",
   "class": "citation-integrity/collective-author",
   "location": "REFERENCES #31 (PMID 30688979)",
   "old": "31.  , Williamson JD, Pajewski NM et al.",
   "new": "31. SPRINT MIND Investigators for the SPRINT Research Group, Williamson JD, Pajewski NM et al.",
   "evidence": "JAMA 2019;321(6):553-561 collective byline; PubMed CollectiveName field not read by the reference builder."
  },
  {
   "id": 2,
   "severity": "Minor",
   "class": "rendering/empty-DOI",
   "location": "REFERENCES #45 (PMID 9052711)",
   "old": "DOI: . Access: abstract_metadata.",
   "new": "Access: abstract_metadata.",
   "evidence": "PubMed holds no DOI for this record; empty field removed rather than filled."
  }
 ],
 "rejected_findings": [
  "Scope-matched aggregation correctly applied (SC2 Ζ is a different scope; scope-matched subclaims SC3/SC4 both Γ).",
  "v5.claim_form 'phenomenon' warning rejected: claim states initiation plus consequence.",
  "v5.lay_summary FAIL is a v5.4-only check on a v5.3 review.",
  "Momentum 'Mechanistic only' carries required artifact.",
  "Reference titles #11/#56 differ only by PubMed dropping italicised gene names.",
  "Retracted landmarks PMID 24336108 / 29400711 correctly excluded and flagged."
 ],
 "regression_vs_earlier_edition": "none; revision adds only the provenance reconciliation block",
 "divergent_copies_left_untouched": [
  "hsef_v53_popularity_ranks_26_30_2026-10-07/two-hit-vascular-dementia/two-hit-vascular-dementia.review.md"
 ],
 "propagate_to": [],
 "consensus_question": "In humans without amyloid or tau pathology at baseline, does blood-brain barrier or pericyte dysfunction precede and predict the subsequent onset of amyloid and tau accumulation?",
 "sha256_review_md_after": "1fb061be1caf8fa69dfa738b245b19fb7818db4cb608b8f0079098ceff3504f5",
 "bytes_review_md_after": 110568
}