{
  "slug": "vaccine-autism-avoidance",
  "authoring_model": "Sol 6.1",
  "adversarial_reviewer": "Claude Opus 5.5 (Anthropic)",
  "review_date": "2026-10-14",
  "round": 2,
  "level_before": "Α",
  "level_after": "Α",
  "confidence_before": "High",
  "confidence_after": "High",
  "pmids_checked": 66,
  "pmids_failed": 0,
  "claims_spot_checked": 16,
  "claims_failed": 0,
  "findings_by_severity": {
    "Critical": 0,
    "Major": 0,
    "Minor": 4,
    "Editorial": 0
  },
  "findings": [
    {
      "id": "AR-1",
      "severity": "Minor",
      "type": "rendering",
      "location": "throughout",
      "original": "renderer-dropped spaces, e.g. 'aHR0.97 with99% CI0.91-1.03'",
      "corrected": "'aHR 0.97 with 99% CI 0.91-1.03' (~127 instances)",
      "evidence": "Known upstream rendering defect; whitespace-only repair, no numeric or wording change."
    },
    {
      "id": "AR-2",
      "severity": "Minor",
      "type": "citation_rendering",
      "location": "REFERENCES 22, 25, 29, 35",
      "original": "DOI: .",
      "corrected": "No DOI in PubMed record.",
      "evidence": "PubMed records for PMID 14595043, 16733480, 18404135, 21225508 carry no DOI element."
    },
    {
      "id": "AR-3",
      "severity": "Minor",
      "type": "status_flags",
      "location": "evidence cards [4], [22], [39], [45], [54], [55]",
      "original": "ErratumIn: PMIDnot supplied. / ErratumIn: PMID26757477.",
      "corrected": "Erratum in: <journal citation> (no PMID in the PubMed record). / Erratum in: <citation> (PMID 26757477).",
      "evidence": "ErratumIn elements for PMID 14595043, 10404911, 8538705, 9682390 contain RefSource only, no PMID; Jain 2015 and Gadad 2015 errata are PMID 26757477 and 26621718."
    },
    {
      "id": "AR-4",
      "severity": "Minor",
      "type": "scoring_text",
      "location": "scorecard final_score.confidence_rationale",
      "original": "density, heterogeneous controls and incomplete access set the confidence, not correctness.",
      "corrected": "evidence density, replication across independent designs and heterogeneous controls set the confidence, not correctness and not reviewer access depth.",
      "evidence": "hsef-framework.md, Confidence band: 'Confidence reflects evidence density and reproducibility.' Band unchanged (High)."
    }
  ],
  "rejected_findings": [
    "Headline Alpha argued up to Beta: rejected, cap 2 is a ceiling not an earned rung.",
    "SC4 Eta: rejected, independence basis passes the v5.2 shared-failure test; Theta correctly withheld.",
    "Aggregation: primary-subclaim pre-registered; weakest-link and scope-matched both also return Alpha; derivation wording correct.",
    "Best-supported rival renderer defect: does not fire; models_evaluated[0] is rank 1 and is_nominal false.",
    "Momentum boilerplate: value is 'Associational only' with a named artifact.",
    "Collective-author defect: none; no reference begins with a stray comma.",
    "Rubric-07 psychiatry hard rules quoted verbatim but declared not triggered; cap-precedence obligation met.",
    "Retracted PMID 21058170 and the 1998 Wakefield report correctly excluded from sources_total.",
    "False-approval boilerplate and REVIEWER NOTES/Consensus contradiction: absent from this package.",
    "Print/e-pub year plus-or-minus 1 differences and PubMed title-case normalisation: rejected per convention."
  ],
  "residual_limitations": [
    "55 of 62 records accessed at abstract/status depth; numeric claims confirmed against abstracts, not full reports.",
    "Four errata without PubMed identifiers remain unexamined in substance.",
    "provenance_header.generated_by reads 'Codex; HSEF v5.3' rather than naming Sol 6.1 (package-wide field, left for the lead)."
  ],
  "validator": {
    "result": "FAIL",
    "fails": 1,
    "warns": 0,
    "passes": 32,
    "detail": "v5.lay_summary only: shipped validator enforces the v5.4 lay-summary rule against a self-declared v5.3 review. Cross-version artifact.",
    "pre_review_validator": "none present in package"
  },
  "files_changed": [
    "vaccine-autism-avoidance.review.md",
    "vaccine-autism-avoidance.scorecard.json",
    "validator.txt"
  ],
  "consensus_questions": [
    "Do prospectively validated individual-level vaccine exposure studies (matched formulation/dose or age-landmark designs) ever report a positive association between childhood vaccination and incident autism diagnosis?",
    "Does loss or refusal of routine childhood immunisation measurably increase laboratory-confirmed measles and pertussis incidence at the individual level?"
  ]
}