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Source and license notes supplied with these plates. Plate inclusion does not add a study to the review or change its evidence rating.
Sourced imagery — cancer-immunoediting academic infographics
Compiled 2026-10-10. All figures come from papers cited in reviews/cancer-immunoediting.html,
verified CC BY / CC BY 4.0 via Europe PMC and the PMC article pages. No fabricated content.
Molecular structures — PDB entries (kept)
PDB coordinate files are public domain per wwPDB policy. Both were rendered in-house (CA-trace cartoons) from the coordinates; the renderings are original.
| File | Structure | Deposition paper | Method / resolution |
|---|---|---|---|
sourced/1HLA.pdb → sourced/pdb-1HLA-hla.png |
Human class I histocompatibility antigen HLA-A2 with beta-2 microglobulin | Saper MA, Bjorkman PJ, Wiley DC. "Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution." J Mol Biol. 1991 | X-ray, 3.5 Å (as deposited) |
sourced/4ZQK.pdb → sourced/pdb-4ZQK-pd1pdl1.png |
Complex of human programmed death-1 (PD-1) and its ligand PD-L1 | Zak KM, Kitel R, Przetocka S, et al. "Structure of the complex of human programmed death 1, PD-1, and its ligand PD-L1." Structure. 2015 | X-ray, 2.45 Å |
Published figures (kept)
McGranahan N, Rosenthal R, Hiley CT, et al. "Allele-Specific HLA Loss and Immune Escape
in Lung Cancer Evolution."
- Journal: Cell 171(6):1259–1271 (2017). DOI: 10.1016/j.cell.2017.10.001. PMCID: PMC5720478. License: CC BY 4.0 ("This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)").
| File | Figure | What it shows |
|---|---|---|
sourced/cell-Fig2EH-trees.png |
Fig. 2, panels E–H (cropped) | Tumor phylogenetic trees: HLA loss of heterozygosity arises subclonally and is enriched in metastases |
sourced/cell-Fig5B-IHC.png |
Fig. 5, panel B (cropped) | H&E and anti-PD-L1 staining of tumors with no HLA LOH vs clonal HLA LOH |
Figure files downloaded from the PMC image CDN
(e.g. https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c3e/5720478/91df422db6aa/gr2.jpg).
Enfield KSS, Colliver E, Lee C, et al. "Spatial Architecture of Myeloid and T Cells
Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer."
- Journal: Cancer Discovery 14:1018–1047 (2024). DOI: 10.1158/2159-8290.CD-23-1380. PMCID: PMC11145179. License: CC BY 4.0 ("distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license").
| File | Figure | What it shows |
|---|---|---|
sourced/candisc-Fig1D-IMC.png |
Fig. 1, panel D (cropped) | Imaging mass cytometry: multiplexed single-cell spatial images of the lung tumor microenvironment (T cells, macrophages, tumor cells, stroma) |
Figure file downloaded from the PMC image CDN
(https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5e/11145179/816ba4df1ce3/1018fig1.jpg).
Rejected candidates (not kept)
| Candidate | Why rejected |
|---|---|
| McGranahan et al. Fig. 1 (LOHHLA algorithm schematic) | Method diagram, not real data |
| McGranahan et al. Fig. 6 (model of HLA allele-specific loss) | Author-drawn model diagram, not real data |
| Wikimedia Commons T-cell / PD-1 illustrations | License verification inconclusive; PDB renders + cited figures cover the content |
| PMC11129594 (immune-tumor spatial evolution, CC BY, cited) | Overlaps the kept Cancer Discovery IMC source; kept source covers spatial evidence more directly |
Notes
- The PDB renders are original CA-trace cartoons; coordinates are public domain.
- If the site displays these, include the attribution lines printed on the graphics adjacent to each image.